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Winning the war against polio

Poliomyelitis, commonly known as polio, is a highly infectious condition caused by the Poliovirus. Children under the age of five are most often affected.

The Poliovirus is mainly spread by person-to-person contact, but can also be transferred via eating raw or undercooked food or water that’s been contaminated with the faeces of an infected person.

Most people with polio don’t experience noticeable signs. The most common indication of polio is a sudden weakness or lameness in the limbs. People who have symptoms may have minor issues like fever, fatigue, nausea, headache, a sore throat, coughing, congestion and stiffness and pain in the arms, legs, back and neck.

The majority of those who contract polio recover completely, but in extreme cases, it causes the permanent loss of muscle function, which may result in paralysis, usually in the arms or legs. It may also cause death if it decreases muscle function used for breathing or if the virus infects your brain.

Polio today

Thankfully, due to routine immunisations, South Africa has been free from polio since 1989. There are, however still cases of polio in other countries. Globally, most countries are polio-free, except for Afghanistan, Nigeria, Pakistan and certain areas in Asia. In recent years, the number of people affected by polio has decreased, but unfortunately, even a small number of infected people can put many others at risk.

What’s worrying is that the poliovirus can easily spread from an infected country to a polio-free one.

What can you do to fight polio?

Unfortunately, there’s no cure for polio, so the only way to fight it is with prevention. To fight polio you should:

Keep up with vaccinations

Ensure you have had a polio vaccination. An additional one-time polio vaccine booster is recommended for those travelling to high-risk countries. To be safe, ask your doctor or nurse if your polio vaccine is up-to-date before travelling. It’s also important to ensure your children are vaccinated. Kids should be immunised with polio drops at birth, six weeks, 10 weeks, 14 weeks, 18 months and when they’re five years old.

Watch your food

Make sure your food is always cooked properly before eating it and avoid raw food. Street vendors in some developing countries may not be safe, so always be cautious. Bushmeat is especially risky, so avoid eating it and don’t drink tap water when travelling, unless it’s been boiled or filtered. Bottled or canned factory drinks are usually safe, but watch out for bottled water that could just be regular tap water.

Practise good hygiene

  • Wash your hands often with warm water and soap. Use hand sanitiser with at least 60% alcohol if there’s no water or soap available.
  • Cover your nose and mouth with a tissue or sleeve if you cough or sneeze.
  • Don’t touch your eyes, nose or mouth. If you do, make sure your hands are clean.
  • Avoid sharing utensils with sick people and avoid close contact (like hugging, holding hands and kissing). 

Good to know

  • Ask your doctor or a nurse at your local clinic or hospital about immunisation and follow the schedule.
  • Immediately report any child under the age of 15 who develops sudden weakness of either an arm and/or leg (without any injury).

References:

Fighting cancer with Polio!

Every year, 12 million people worldwide will hear the words “you have cancer”. There are few illnesses as terrifying as cancer. With one in four South Africans being affected in their lifetime, it is almost impossible to remain untouched by the disease.

Why haven’t we found a cure for cancer?

Cancer starts when cells start to grow abnormally, get out of control and begin to crowd out normal cells. These abnormal cells also start to invade other tissues. Together, this makes it hard for the body to work the way it should.

“Cancer” is not just one disease, it’s a group of over 100 different conditions. While there are some similarities between the different types of cancer, there are also many differences. This is one of the main reasons that experts have yet to identify an umbrella “cure” for the disease. That’s not to say they aren’t trying! Every year, new research and techniques are developed that bring us one step closer to conquering the condition. The most recent discovery: using Polio cells to fight off cancer.

Why use polio to fight cancer?

Researchers have discovered, using mice cells, that polio can trigger an immune system reaction that not only destroys cancerous tumour growth, but also stops tumours from coming back.

How does it work?

Polio is a virus, which means it invades other cells and takes over that cell’s operating machinery. Some cancerous cells have a specific protein that acts as a “receptor” for the polio virus. That means that the polio virus is attracted to these cells and can invade them. In this experiment, the researchers identified two ways in which polio initiates an attack on the cancer cells.

Once the polio virus invaded the cancerous cells, they started producing substances called “antigens”, or toxins that the body doesn’t recognise which initiated an initial immune response. At the same time, the polio virus infected helper cells of the immune system. These infected cells activated a direct attack on the cancerous cells, and triggered the release of macrophages, whose job it is to rid the body of any debris and foreign substances.

These two processes destroyed the tumour, and weakened the cancerous cells which stopped them from regrowing.

Isn’t polio dangerous?

In its original form, yes! But scientists have created a so called “Frankenstein” version of the virus. They managed to break the polio virus down into its basic elements. Then they took out the “dangerous” piece, and replaced it with a harmless piece. This new modified virus can’t cause paralysis or death because it can’t reproduce in normal cells. But in cancer cells it does and, in the process of replicating, it releases the toxins that poison the cell.

What does this mean to you?

This is certainly a ground-breaking, and very promising, discovery but don’t expect to be able to get your Frankenstein-Polio jab at your local pharmacy any time soon. The findings of this study provide only a basis for further clinical trials and a new avenue to explore in the fight against cancer.

In the meantime, there is much that you can do to lower your risk of cancer. It is estimated that most cancer cases are caused by certain lifestyle choices. Of course, choosing a healthy lifestyle is not a 100% guarantee against ever being diagnosed with cancer, but it does significantly improve your odds! Here is what you can do:

  • Don’t smoke. Ever. If you do, consider giving up ASAP
  • Eat a healthy diet. This includes limiting all processed foods, and increasing fresh produce
  • Maintain a healthy weight. Obesity is an important risk factor not only for cancer, but for several other health conditions too
  • Every day if you can!
  • Stay safe in the sun. Use sunblock every day, cover up and stay indoors over peak hours (11am-3pm)
  • Avoid risky behaviours. Always practise safe sex and never share needles
  • Know your health! Get regular check-ups. Contact one of our doctors who can talk you through what tests are recommended for your age and gender

References

https://www.medicalnewstoday.com/articles/319467.php

Why polio vaccines still matter

Polio – didn’t that disease die out with snail-mail and telex machines? Today is World Polio Day and, no – polio is still happening out there.

In March of 2014 the World Health Organisation (WHO) raised the risk assessment of international spread of polio from central Africa – particularly Cameroon – to very high. Continue reading “Why polio vaccines still matter”

Polio still not dead

While polio may seem like history for most of the world, it’s still very much alive in countries like Nigeria, Pakistan and Afghanistan, but a new study may have found a way to eradicate the disease for good. The study suggests that giving vaccinated children an extra dose of inactivated polio vaccine could boost their immunity and help eradicate the highly infectious disease.

Continue reading “Polio still not dead”